Upper Respiratory Infections in CatsCat Upper Respiratory Infection Treatment in Apopka, FL

Upper respiratory infections (URIs) are among the most common illnesses in cats, especially in multi-cat households, shelters, and newly adopted kittens. While often referred to as “cat colds,” URIs can range from mild to serious — and some cats develop chronic, recurring infections. At Pet Xpert Animal Clinic in Apopka, FL, Dr. Alex can evaluate your cat’s symptoms and provide the appropriate treatment to help them recover comfortably. Call (407) 886-7387 to schedule an appointment.

What Causes Upper Respiratory Infections in Cats?

The majority of feline URIs are caused by one of two viral pathogens: Feline Herpesvirus (FHV-1) and Feline Calicivirus (FCV). Both are highly contagious between cats and are transmitted through direct contact with secretions from the eyes, nose, and mouth, as well as through shared food bowls, litter boxes, and contaminated surfaces. FHV-1 is particularly significant because it establishes a lifelong latent infection — stressed cats can experience recurrent outbreaks throughout their lives.

Secondary bacterial infections frequently complicate viral URIs, turning a self-limiting cold into a more prolonged illness requiring antibiotic therapy. Signs of a URI include:

  • Sneezing and nasal discharge (clear, yellow, or green)
  • Eye discharge or conjunctivitis
  • Decreased appetite (cats rely heavily on smell to stimulate eating)
  • Lethargy and general malaise
  • Mild fever
  • In severe cases, mouth sores (more common with calicivirus)

Vaccination with the FVRCP vaccine provides protection against both FHV-1 and FCV. While it may not completely prevent infection, it significantly reduces severity. See our cat vaccination page for information on keeping your cat’s vaccines current. Treatment of active URIs is largely supportive — antibiotics for secondary bacterial infections, nutritional support, and keeping nasal passages clear. Severely affected cats, particularly kittens, may need hospitalization for fluids and more intensive care.

Cat URI FAQs

Are upper respiratory infections in cats contagious to other cats?

Yes — feline URIs are highly contagious between cats. Viral and bacterial pathogens are shed in nasal, ocular, and oral secretions and can be spread through direct contact or contaminated objects. If one cat in a multi-cat household is diagnosed, it’s important to isolate the sick cat and take precautions to prevent spreading infection to other cats.

Can humans catch a cold from a cat with a URI?

The viruses that cause most feline URIs (herpesvirus and calicivirus) are species-specific and cannot infect humans. However, some bacterial causes of URIs — such as Chlamydia felis — can rarely cause mild conjunctivitis in humans who handle infected cats. Basic hygiene, including hand-washing after handling a sick cat, is always recommended.

How long does a cat URI typically last?

Uncomplicated viral URIs typically resolve within 7–14 days with supportive care. Cases complicated by secondary bacterial infections may take longer. Cats with herpesvirus may experience recurrent episodes throughout their lives, particularly during periods of stress. Recurrent or severe URIs warrant veterinary evaluation and may benefit from specific antiviral support.

My cat stopped eating during their URI. Should I be concerned?

Yes — a cat that stops eating for more than 24–48 hours is a concern, both because of the URI itself and because of the risk of hepatic lipidosis (fatty liver disease), which can develop rapidly in cats that don’t eat. If your cat is refusing food, contact Pet Xpert Animal Clinic at (407) 886-7387 promptly. Warming food, offering strong-smelling options, and clearing nasal congestion can help stimulate appetite.

Can vaccines prevent URIs in cats?

The FVRCP vaccine protects against feline herpesvirus and calicivirus — the two most common URI pathogens. While vaccination may not prevent infection entirely, it significantly reduces the severity and duration of illness in vaccinated cats. Keeping your cat up to date on vaccinations is an important part of URI prevention. Ask Dr. Alex about your cat’s vaccination status at their next visit.

My cat had a URI as a kitten and keeps getting sick. Is this normal?

Recurrent URIs in adult cats are often due to latent herpesvirus infection established during the initial illness. Stress, illness, or immune suppression can trigger reactivation. Management strategies include minimizing stress, maintaining excellent nutrition, and in some cases, supplementing with L-lysine (discuss with Dr. Alex). Cats with very frequent or severe recurrences may benefit from additional evaluation and targeted support.

Should I keep my cat with a URI away from other pets?

Yes. Cats with active URIs should be separated from other cats in the household to minimize spread. Wash your hands thoroughly after handling the sick cat before touching other pets. Disinfect shared surfaces, food bowls, and litter boxes. Continue isolation until the sick cat has been symptom-free for at least a week, as they may still be shedding virus during recovery.